Onychodystrophy Testing
Histopathology + PCR = The Complete Picture
Various nail disorders appear identical and clinical examination alone may not be enough.
Definitive Diagnosis
Laboratory testing identifies the underlying cause of nail dystrophy – infectious, non-infectious, neoplastic processes, and trauma
Complete Picture
Histopathology + PCR Testing provide comprehensive information to treat nail dystrophy effectively.
Targeted Treatment
Identifying the genus and species of the infectious organism allows you to target therapy with precision.
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The Complete Picture
*When used in combination; Bako Nail PCR Testing: 99.9% Analytical Specificity, 86% Clinical Sensitivity. Bako’s PCR testing highly correlates with histopathology. Histopathology: 93% Clinical Sensitivity, 96% Clinical Specificity. Fungal culture: 42% False Negative Rates
Histopathology
Microscopic evaluation of a specimen to determine infectious or non-infectious pathologies including traumatic, inflammatory or neoplastic processes.
Periodic Acid–Schiff (PAS): Identifies non-degenerated fungal elements
Grocott Methenamine Silver (GMS): Identifies degenerated fungal elements
Fontana-Masson (FM): Identifies pigmented saprophytes and melanin pigment which may be associated with a melanocytic neoplasm
PCR
Molecular analysis of a specimen to determine if DNA of an infectious organism is present.
Onychodystrophy PCR Test: Identifies genus and species of most common fungi (dermatophytes, saprophytes, and yeasts) as well as the bacteria, pseudomonas aeruginosa, that cause nail dystrophy
PCR with Terbinafine Resistance Reflex: When positive for T. rubrum or T. mentagrophytes, detects mutations associated with terbinafine resistance
Educational Resources for Onychodystrophy
Disclaimer: BakoDx, as a partner to your practice, provides learning resources to help you better serve your patients. The information contained within this document should be used at a physician’s discretion. BakoDx assumes no liability for its content.