Onychodystrophy Testing

Histopathology + PCR = The Complete Picture

Various nail disorders appear identical and clinical examination alone may not be enough.

Definitive Diagnosis

Definitive Diagnosis

Laboratory testing identifies the underlying cause of nail dystrophy – infectious, non-infectious, neoplastic processes, and trauma

Complete Picture

Complete Picture

Histopathology + PCR Testing provide comprehensive information to treat nail dystrophy effectively.

Targeted Treatment

Targeted Treatment

Identifying the genus and species of the infectious organism allows you to target therapy with precision.

Learn more about adding Onychodystrophy testing to your patient care algorithm

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The Complete Picture

  • Speciation for Targeted Treatment
  • Terbinafine Resistance for Treatment Efficacy
  • Identification of Non-Infectious and Infectious Causes
  • Highest Sensitivity and Specificity Testing Available*
  • Rapid results

*When used in combination; Bako Nail PCR Testing: 99.9% Analytical Specificity, 86% Clinical Sensitivity. Bako’s PCR testing highly correlates with histopathology. Histopathology: 93% Clinical Sensitivity, 96% Clinical Specificity. Fungal culture: 42% False Negative Rates

Test Comparison

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Histopathology Microscope


Microscopic evaluation of a specimen to determine infectious or non-infectious pathologies including traumatic, inflammatory or neoplastic processes.

Periodic Acid–Schiff (PAS): Identifies non-degenerated fungal elements

Grocott Methenamine Silver (GMS): Identifies degenerated fungal elements

Fontana-Masson (FM): Identifies pigmented saprophytes and melanin pigment which may be associated with a melanocytic neoplasm

Anatomic Pathology Services


Molecular analysis of a specimen to determine if DNA of an infectious organism is present.

Onychodystrophy PCR Test: Identifies genus and species of most common fungi (dermatophytes, saprophytes, and yeasts) as well as the bacteria, pseudomonas aeruginosa, that cause nail dystrophy

PCR with Terbinafine Resistance Reflex: When positive for T. rubrum or T. mentagrophytes, detects mutations associated with terbinafine resistance

PCR + Terbinafine Resistance Test
BakoDx Sample Report

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BakoDx’s Intelligent Onychodystrophy PCR Testing Report

Actionable reports with information to assist you in making treatment decisions.

  • Diagnosis

  • Treatment Recommendations

  • Relevant Clinical Images

  • Interpretations for All Tests Performed

  • Pathologists Available for Consult

Get Started with Onychodystrophy Testing

Educational Resources for Onychodystrophy

Nail Collection Guide

Optimal Nail Specimen Procedure Guide. Download this easy-to-follow training tool for your staff.

View Nail Collection Guide
BakoDx Clinical White Paper

DNA-based detection for onychomycosis correlates better to histopathology than does fungal culture.

Read Clinical Study
Nail Collection Guide

Reference this hands-on, procedural video created by BakoDx clinical consultants.

Watch Procedural Video

Disclaimer: BakoDx, as a partner to your practice, provides learning resources to help you better serve your patients. The information contained within this document should be used at a physician’s discretion. BakoDx assumes no liability for its content.