Histopathology + PCR = The Complete Picture
Various nail disorders appear identical and clinical examination alone may not be enough.
Laboratory testing identifies the underlying cause of nail dystrophy – infectious, non-infectious, neoplastic processes, and trauma
Histopathology + PCR Testing provide comprehensive information to treat nail dystrophy effectively.
Identifying the genus and species of the infectious organism allows you to target therapy with precision.
Learn more about adding Onychodystrophy testing to your patient care algorithm
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The Complete Picture
- Speciation for Targeted Treatment
- Terbinafine Resistance for Treatment Efficacy
- Identification of Non-Infectious and Infectious Causes
- Highest Sensitivity and Specificity Testing Available*
- Rapid results
*When used in combination; Bako Nail PCR Testing: 99.9% Analytical Specificity, 86% Clinical Sensitivity. Bako’s PCR testing highly correlates with histopathology. Histopathology: 93% Clinical Sensitivity, 96% Clinical Specificity. Fungal culture: 42% False Negative Rates
Microscopic evaluation of a specimen to determine infectious or non-infectious pathologies including traumatic, inflammatory or neoplastic processes.
Periodic Acid–Schiff (PAS): Identifies non-degenerated fungal elements
Grocott Methenamine Silver (GMS): Identifies degenerated fungal elements
Fontana-Masson (FM): Identifies pigmented saprophytes and melanin pigment which may be associated with a melanocytic neoplasm
Molecular analysis of a specimen to determine if DNA of an infectious organism is present.
Onychodystrophy PCR Test: Identifies genus and species of most common fungi (dermatophytes, saprophytes, and yeasts) as well as the bacteria, pseudomonas aeruginosa, that cause nail dystrophy
PCR with Terbinafine Resistance Reflex: When positive for T. rubrum or T. mentagrophytes, detects mutations associated with terbinafine resistance
Educational Resources for Onychodystrophy
Disclaimer: BakoDx, as a partner to your practice, provides learning resources to help you better serve your patients. The information contained within this document should be used at a physician’s discretion. BakoDx assumes no liability for its content.